Four detectives in four different eras find the body of the same murder victim in London's Whitechapel. Edmon Hillinghead is the town's most diligent detective in 1890 as Jack the Ripper prowls the streets. In 1941, Charles Whiteman rules the streets by spearheading the cons he's supposed to put down. Shahara Hasan battles racist rioters in 2023, and in the year 2053, young Maplewood struggles with amnesia as one of the last survivors of a terrifying techno-apocalypse. During their investigation, the foursome discover they are dealing with a mysterious conspiracy that spans over 150 years.