Richard Sackler comes from a billionaire family that runs Purdue Pharma. The company has enjoyed great success with the production and release of Oxycontin, a strong painkiller, after it becomes the leading opioid in the country. Due to the addictive effect of the painkiller, an opioid crisis is emerging in America. Many lives are destroyed and Edie Flowers, a lawyer, wants to prosecute Purdue Pharma as a prosecutor. She is determined to put an end to the company and its founder.