The Knife plot
"Presents a startling but effeacious remedy for social ills."
Kate Tarleton grows up on a southern plantation and becomes engaged to her guardian, Dr. Robert Manning, a famous surgeon. When Robert, Kate, and her younger sister Mary Lou visit New York, where the doctor plans to conduct medical experiments, the superstitious Kate goes to the home of a fortune teller named Stella Hill. Stella, whose main business is trading slaves, drugs Kate and forces her to work in a "den of vice" run by Stella and her accomplice Jimmy Bristol, where she contracts syphilis and goes mad.