IRIS is about the single, female veterinarian Iris de Weerdt. She has now found her niche in the village of Rodenburg. Her converted farm-cum-practice is the center of daily recurring problems and in addition to her work, Iris stands up for the interests of fellow villagers in municipal politics and fights against political scheming. Despite her busy life, Iris finds her great love, but it turns out to be far from uncomplicated.