In 'Brain Man' Otto-Jan Ham investigates whether it is possible to improve the functioning of your brain. If so, how do you do that? And how far do you want to go with that? To find answers to these questions, Otto-Jan subjects himself as a guinea pig to a series of daring experiments. He is assisted by his Woestijnvis colleague Bart Van Peer. Bart is a scientist by training and has been fascinated by new developments in neuroscience for years. Together they provide a unique combination of science and humor.